Elevated leukocytes in psoriasis

Psoriasis, known as psoriasis, is a chronic inflammation in the human organism. Thus, the leukocytes known as inflammatory markers occur in high concentrations in psoriasis.

Psoriasis is a skin disease. It is usually considered hereditary but not contagious. Psoriasis mainly affects the skin areas on the hands, joints and elbows.

The nails are also affected in half of the patients. In particular, the leukocytes play a major role in psoriasis. White blood cells accumulate in the foci of disease in the body. Here, the T-leukocytes occur in high concentrations. Based on this observation, doctors assume that there is a connection between the disease and the patient’s immune system.

Psoriasis and the immune system

Some doctors refer to psoriasis as an immune reaction. Autoimmune T cells influence this response. The immune system reacts to the tissue of the organism as if it were a foreign body. It attacks him and produces numerous leukocytes in return.

The white blood cells attack the body’s own tissues. Inflammation occurs, whereupon the organism forms more and more leukocytes. Accordingly, there is an interaction between the leukocytes and the psoriasis.

Psoriasis and white blood cells

Patients suffering from psoriasis suffer from a red, usually itchy rash. The skin visibly flakes off, resulting in a white crust. There is pus in these blisters. The increased leukocytes in psoriasis develop as a result of this chronic inflammation inside the body. They accumulate in the top layer of skin. Doctors call this the epidermis. If there is a strong accumulation of white blood cells, the typical psoriasis rash follows. The leukocytes thus serve as disease markers in the blood and at the same time lead to a visible characteristic of the disease.

The different forms of the disease

Type one and type two of psoriasis are known. In type one of the disease, those affected notice the first signs between the ages of 15 and 25. This type of psoriasis in particular appears to be hereditary. Many sufferers have parents or grandparents who also have the disease. A specific antigen shows up as a clear symptom of heredity. This is found on the white blood cells.

Type two of psoriasis occurs after the age of 40. The rash usually does not cover the entire body. Instead, it spreads more easily. The nails and joints are among the most common areas of scale formation. This form of the disease has no connection with heredity. There is therefore no antigen that indicates a hereditary disease.

The severe form of psoriasis

The worse the inflammation spreads in the body, the higher the leukocyte concentration in the blood rises. In a severe form of the disease, the deposits of leukocytes in psoriasis appear all over the body. This type of disease is more common in women. Smokers in particular have a higher risk of suffering from psoriasis. Doctors speak of this disease as pustulosageneralisata psoriasis. Another technical term is Type Zumbusch. Other symptoms of this include:

• Fever,
• Fatigue,
• a feeling of exhaustion
• and a general feeling of illness.

Predominantly the rapidly and aggressively spreading rash impairs the function of the skin. This severe form of psoriasis can be life-threatening for those affected.

What triggers a flare-up?

There are various factors that cause psoriasis to flare up. These are mainly complications that contribute to an increase in leukocytes. For example, cold weather makes the rash more severe. This is because the body creates more leukocytes due to infections. Due to the constant accumulation in the epidermis, these cause stronger skin irritation. Furthermore, the concentration of white blood cells increases during operations or general anesthesia. Again, the leukocytes affect psoriasis.

Other factors that lead to an flare-up of the disease show up in the form of alcohol, nicotine and stress. The situation is similar with medicines for internal use. The white blood cells in the organism react to these triggers. Doctors also observe the body’s reaction to burns or mechanical stimuli. In some cases, pregnancy or menopause trigger a more severe form of psoriasis.

The increased leukocytes and psoriasis influence each other. The chronic inflammation inside the body increases the concentration of white blood cells. Deposits in the epidermis result in the rash typical of psoriasis.